MHC Class II (I-A/I-E) Rat anti-Mouse, Clone: M5/114.15.2, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-5321-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15218647

Quantity Price
1 £ 54.42 / 50µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Host Species Rat
Applications Flow Cytometry
Applications Functional Assay
Clone M5/114.15.2
Formulation aqueous buffer, no sodium azide
Primary or Secondary Primary
Format Purified
Gene Alias MHC II, IA, IE, I-A/E, IA/IE
Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal
Conjugate Unlabeled
Concentration 1mg/mL
Species Reactivity Mouse
Isotype IgG2b
Quantity 50μg
Antigen MHC Class II (I-A/I-E)
Regulatory Status RUO

The M5/114.15.2 monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.