MHC Class II (I-A/I-E) Rat anti-Mouse, Clone: M5/114.15.2, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5321-85

Product Code. 15237417

Disclaimers:

For Research Use Only.

Description

The M5/114.15.2 monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.

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Specifications

• Antigen: MHC Class II (I-A/I-E)
• Clone: M5/114.15.2
• Conjugate: Unlabeled
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Host Species: Rat
• Quantity: 500μg
• Storage Requirements: Store at 2-8°C.
• Monoclonal or Polyclonal: Monoclonal

• Applications: Western Blot
• Concentration: 0.5mg/mL
• Format: Purified
• Gene Alias: MHC II, IA, IE, I-A/E, IA/IE
• Isotype: IgG2b
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Murine