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Mevastatin, Tocris Bioscience™

HMG-CoA reductase inhibitor

Brand:  Tocris (Bio-Techne) 152650

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13429613

  • £366.03 / 50mg

Estimated Shipment date
from Supplier 06-04-2020

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Description

Description

Inhibitor of HMG-CoA reductase; decreases cholesterol biosynthesis, in vitro and in vivo. Induces apoptosis, arrests cancer cells in G1 phase and downregulates cdk 2, 4, and 6, cyclin D1 and E1, p21 and p27. Inactive lactam prodrug of mevastatin hydroxy acid, naturally bioactivated in vivo following oral administration.
Specifications

Chemical Identifiers

73573-88-3
390.52
mevastatin, compactin, mevastatinum, mevastatina, mevastatine, mevastatinum inn-latin, antibiotic ml 236b, mevastatin inn, compactin penicillium, mevastatine inn-french
CHEBI:34848
CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O
C23H34O5
AJLFOPYRIVGYMJ-INTXDZFKSA-N
64715
[(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate

Specifications

50mg
73573-88-3
mevastatin, compactin, mevastatinum, mevastatina, mevastatine, mevastatinum inn-latin, antibiotic ml 236b, mevastatin inn, compactin penicillium, mevastatine inn-french
CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O
390.52
CHEBI:34848
>98%
Mevastatin
C23H34O5
AJLFOPYRIVGYMJ-INTXDZFKSA-N
[(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
64715
390.52
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