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Methotrexate, Fisher BioReagents

Brand:  Fisher Bioreagents BP2665-10

UNSPSC : 12350000

Code : 32

Additional Details : CAS Number : 59-05-2 Weight : 0.05001kg Transport : UN number : 2811 Chem class : 1 Pack group : III


Quantity 10mg
Packaging Amber Glass

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Product Code. 10705304

  • £47.60 / 10mg


Estimated Shipment
13-09-2017
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Description

Description

  • Inhibitor of DNA and RNA synthesis
  • Inhibits the enzyme responsible for synthesizing the folic acid derivative that is necessary for purine and pyrimidine synthesis
  • The lack of purines and pyrimidines  impacts the synthesis of DNA, RNA, and proteins
  • Referenced for use in antitumor studies and other studies of biological pathways
  • Intended for research use only
Specifications

Chemical Identifiers

Methotrexate
Powder/Solid
98.0 to 102.0 %
454.44
59-05-2
98.0 to 102.0%
C20H22N8O5
Amethopterin

Specifications

Methotrexate
Meets Requirements
0.1% max.
+19.0 to +24.0° (+ or -)
98.0 to 102.0%
C20H22N8O5
454.44
15, 6057
Yellow
10mg
59-05-2
Amber Glass
Pass Test
Powder/Solid
98.0 to 102.0 %
12% Max.
>195°C
Amethopterin
195°C
Safety and Handling

Safety and Handling

Product Identifier
  • Methotrexate

Signal Word
  • Danger

Hazard Category
  • Acute toxicity Category 3
  • Serious eye damage/eye irritation Category 2
  • Germ cell mutagenicity Category 1B
  • Reproductive toxicity Category 1B
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3

Hazard Statement
  • H340-May cause genetic defects.
  • H360FD-May damage fertility. May damage the unborn child.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
  • H301-Toxic if swallowed.

Precautionary Statement
  • P281-Use personal protective equipment as required.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.

Documentation