Methotrexate, Fisher BioReagents


Overview
Brand: Fisher Bioreagents

Manufacturer Part Number: BP2665-10

10MG Methotrexate (Yellow Powder), 98.0 to 102.0 %

UNSPSC: 12350000

Code: 32

Additional Details:
Additional Details: CAS Number: 59-05-2 Weight: 0.05001kg Transport: UN number : 2811 Chem class : 1 Pack group : III


Packaging Amber Glass
Quantity 10mg

Product Code. 10705304

Quantity Price
1 £ 47.6 / 10mg
EU Stock 1
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Description and Specification

Chemical Identifiers

Chemical Name or Material Methotrexate
CAS 59-05-2
Physical Form Powder/Solid
Assay 98.0 to 102.0%
Assay Percent Range 98.0 to 102.0 %
Molecular Formula C20H22N8O5
Formula Weight 454.44
Synonym Amethopterin

Specification

Physical Form Powder/Solid
Formula Weight 454.44
Melting Point 195°C
Quantity 10mg
Merck Index 15, 6057
DOT Information DOT Class 6.1, : Poison
Assay 98.0 to 102.0%
Specific Rotation +19.0 to +24.0° (+ or -)
Decomposition Information >195°C
Health Hazard 3 Emergency Overview
Toxic if swallowed. This substance has caused adverse reproductive and fetal effects in humans. May cause heritable genetic damage. Liver and kidney injuries may occur. Hygroscopic. Use only under a chemical fume hood. Use personal protective equipment. Do not breathe dust. Do not get in eyes, on skin, or on clothing. Wash off immediately with plenty of water for at least 15 minutes. Obtain medical attention. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Obtain medical attention.

NFPA

Health:3
Flammability:0
Instability:1
CAS 59-05-2
ChemAlert Storage Symbol Blue
Recommended Storage 0°C
Organic Volatile Impurities Meets Requirements
Purity Pass Test
Assay Percent Range 98.0 to 102.0 %
Packaging Amber Glass
Ignition Residue 0.1% max.
Water 12% Max.
Health Hazard 2 DANGER!
Molecular Formula C20H22N8O5
Color Yellow
Chemical Name or Material Methotrexate
Synonym Amethopterin

  • Inhibitor of DNA and RNA synthesis
  • Inhibits the enzyme responsible for synthesizing the folic acid derivative that is necessary for purine and pyrimidine synthesis
  • The lack of purines and pyrimidines  impacts the synthesis of DNA, RNA, and proteins
  • Referenced for use in antitumor studies and other studies of biological pathways
  • Intended for research use only

Documentation Safety and Handling
ChemAlertStorageSymbol : Blue

DANGER!

Emergency Overview
Toxic if swallowed. This substance has caused adverse reproductive and fetal effects in humans. May cause heritable genetic damage. Liver and kidney injuries may occur. Hygroscopic. Use only under a chemical fume hood. Use personal protective equipment. Do not breathe dust. Do not get in eyes, on skin, or on clothing. Wash off immediately with plenty of water for at least 15 minutes. Obtain medical attention. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Obtain medical attention.

NFPA

Health:3
Flammability:0
Instability:1

0°C