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Methotrexate, Fisher BioReagents
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Quantity:
10 mg
100 mg
Packaging:
Amber Glass
Description
- Inhibitor of DNA and RNA synthesis
- Inhibits the enzyme responsible for synthesizing the folic acid derivative that is necessary for purine and pyrimidine synthesis
- The lack of purines and pyrimidines impacts the synthesis of DNA, RNA, and proteins
- Referenced for use in antitumor studies and other studies of biological pathways
- Intended for research use only
Specifications
Decomposition Information | >195°C |
Melting Point | 195°C |
Color | Yellow |
Ignition Residue | 0.1% max. |
Assay Percent Range | 98.0 to 102.0 % |
Packaging | Amber Glass |
Quantity | 10 mg |
Merck Index | 15, 6057 |
Specific Rotation | +19.0 to +24.0° (+ or -) |
Formula Weight | 454.44 |
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Safety and Handling
Product Identifier
- Methotrexate
- Danger
- Acute toxicity Category 3
- Serious eye damage/eye irritation Category 2
- Germ cell mutagenicity Category 1B
- Reproductive toxicity Category 1B
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
- H340-May cause genetic defects.
- H360FD-May damage fertility. May damage the unborn child.
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
- H301-Toxic if swallowed.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P308+P313-IF exposed or concerned: Get medical advice/attention.
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