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MC 1568, Tocris Bioscience™

Selective HDAC class II (IIa) inhibitor

Brand:  RD Systems (Bio-Techne) 4077/10

Code : Z1

Additional Details : Weight : 0.00010kg

Quantity 10mg

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Product Code. 13444104

  • £151.41 / 10mg

Estimated Shipment date
from Supplier 16-12-2019

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Description

Description

Selective inhibitor of class IIa histone deacetylases (HDACs). Exhibits tissue-selective inhibition between members of class II deacetylases in vivo; inhibits HDAC4 and HDAC5 in skeletal muscle and the heart without affecting HDAC3 activity. Arrests myogenesis through the stabilization of myocyte enhancer factor 2D (MEF2D)-HDAC3/4 complex. Displays no inhibition of class I HDAC activity or expression.
Specifications

Chemical Identifiers

852475-26-4
314.316
hdac-in-1, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methyl-1h-pyrrol-2-yl-n-hydroxyacrylamide, 2e-3-4-1e-3-3-fluorophenyl-3-oxoprop-1-en-1-yl-1-methylpyrrol-2-yl-n-hydroxyprop-2-enamide, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-en-1-yl-1-methyl-1h-pyrrol-2-yl-n-hydroxyacrylamide, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methylpyrrol-2-yl-n-hydroxyprop-2-enamide, 3-5-3-3-fluorophenyl-3-oxopropen-1-yl-1-methyl-1h-pyrrol-2-yl-n-hydroxy-2-propenamide, mc1568 inverted exclamation marky hplc, 3-4-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methyl-1h-pyrrol-2-yl-n-hydroxyacrylamide, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methyl-1hpyrrol-2-yl-n-hydroxyacrylamide, e-3-4-3-3-fluoro-phenyl-3-oxo-propenyl-1-methyl-1h-pyrrol-2-yl-n-hydroxy-acrylamide
(E)-3-[4-[(E)-3-(3-fluorophenyl)-3-oxoprop-1-enyl]-1-methylpyrrol-2-yl]-N-hydroxyprop-2-enamide
C17H15FN2O3
QRDAPCMJAOQZSU-KQQUZDAGSA-N
11381449
CN1C=C(C=C1C=CC(=O)NO)C=CC(=O)C2=CC(=CC=C2)F

Specifications

10mg
852475-26-4
hdac-in-1, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methyl-1h-pyrrol-2-yl-n-hydroxyacrylamide, 2e-3-4-1e-3-3-fluorophenyl-3-oxoprop-1-en-1-yl-1-methylpyrrol-2-yl-n-hydroxyprop-2-enamide, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-en-1-yl-1-methyl-1h-pyrrol-2-yl-n-hydroxyacrylamide, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methylpyrrol-2-yl-n-hydroxyprop-2-enamide, 3-5-3-3-fluorophenyl-3-oxopropen-1-yl-1-methyl-1h-pyrrol-2-yl-n-hydroxy-2-propenamide, mc1568 inverted exclamation marky hplc, 3-4-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methyl-1h-pyrrol-2-yl-n-hydroxyacrylamide, e-3-4-e-3-3-fluorophenyl-3-oxoprop-1-enyl-1-methyl-1hpyrrol-2-yl-n-hydroxyacrylamide, e-3-4-3-3-fluoro-phenyl-3-oxo-propenyl-1-methyl-1h-pyrrol-2-yl-n-hydroxy-acrylamide
CN1C=C(C=C1C=CC(=O)NO)C=CC(=O)C2=CC(=CC=C2)F
314.316
314.31
MC 1568
C17H15FN2O3
QRDAPCMJAOQZSU-KQQUZDAGSA-N
(E)-3-[4-[(E)-3-(3-fluorophenyl)-3-oxoprop-1-enyl]-1-methylpyrrol-2-yl]-N-hydroxyprop-2-enamide
11381449
>96%
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