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Maraviroc, Tocris Bioscience™

Selective CCR5 antagonist

Brand:  Tocris (Bio-Techne) 375650

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13463554

  • £805.08 / 50mg


Estimated Shipment
02-01-2019
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Description

Description

Selective CCR5 antagonist; displays potent anti-HIV-1 activity. Prevents the interaction of HIV-1 gp120 and CCR5 (IC50 = 6.4 nM), inhibiting HIV-1 entry. Exhibits antinociceptive effects in a rat model of neuropathic pain. Also inhibits CCL3 (MIP-1α) binding to CCR5. Orally bioavailable.
Specifications

Chemical Identifiers

376348-65-1
513.678
maraviroc, selzentry, celsentri, maraviroc usan, celsentri tm, selzentry tm, 3h maraviroc, unii-md6p741w8a, pro 140 & maraviroc, mvc
4,4-difluoro-N-[(1S)-3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide
C29H41F2N5O
GSNHKUDZZFZSJB-HLMSNRGBSA-N
3002977
CC1=NN=C(N1C2CC3CCC(C2)N3CCC(C4=CC=CC=C4)NC(=O)C5CCC(CC5)(F)F)C(C)C

Specifications

Maraviroc
376348-65-1
maraviroc, selzentry, celsentri, maraviroc usan, celsentri tm, selzentry tm, 3h maraviroc, unii-md6p741w8a, pro 140 & maraviroc, mvc
CC1=NN=C(N1C2CC3CCC(C2)N3CCC(C4=CC=CC=C4)NC(=O)C5CCC(CC5)(F)F)C(C)C
513.678
513.67
50mg
C29H41F2N5O
GSNHKUDZZFZSJB-HLMSNRGBSA-N
4,4-difluoro-N-[(1S)-3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide
3002977
>99%
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