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Maraviroc, Tocris Bioscience™

Selective CCR5 antagonist

Brand:  Tocris (Bio-Techne) 375650

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13463554

  • £840.00 / 50mg


Estimated Shipment
28-06-2018
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Description

Description

Selective CCR5 antagonist; displays potent anti-HIV-1 activity. Prevents the interaction of HIV-1 gp120 and CCR5 (IC50 = 6.4 nM), inhibiting HIV-1 entry. Exhibits antinociceptive effects in a rat model of neuropathic pain. Also inhibits CCL3 (MIP-1α) binding to CCR5. Orally bioavailable.
Specifications

Chemical Identifiers

Maraviroc
C29H41F2N5O
513.67
4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl- 5-methyl-4H-1,2,4-triazol-4-yl)- 8-azabicyclo[3.2.1]oct-8-yl]-1- phenylpropyl}cyclohexanecarboxamide

Specifications

Maraviroc
376348-65-1
C29H41F2N5O
4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl- 5-methyl-4H-1,2,4-triazol-4-yl)- 8-azabicyclo[3.2.1]oct-8-yl]-1- phenylpropyl}cyclohexanecarboxamide
50mg
>99%
513.67
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