Thermo Scientific™ Maleimide-Activated Blue Carrier™ Protein

Make hapten-carrier immunogens comprising cysteine-containing peptides and other thiolated antigens with sulfhydryl-reactive immunogenic hemocyanin (CCH).

Brand: Thermo Scientific™

Manufacturer Part Number: 77661

2 MG PIERCE IMJECT MALEIMIDE ACTIVATED BLUE CARRIEr protein2mg Store in freezer at -20°C

UNSPSC: 41106500

Code: PN

Additional Details:
Additional Details: Weight: 0.01000kg

Product Code. 11821184

Quantity Price
1 £56.00 / 2mg
Estimated Shipment date
from Supplier 11-11-2016
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Description and Specification


Description Imject Maleimide-Activated Blue Carrier Protein
Formulation Activated protein lyophilized in 10mM sodium phosphate, 150mM sodium chloride, 10mM EDTA, 50mM sucrose, pH 7.2
Quantity 2mg
Sufficient For 1 conjugation reaction with up to 2mg sulfhydryl-containing peptide
Activation Maleimide
Format Lyophilized
Protein CCH, Concholepas concholepas hemocyanin

Blue Carrier Protein is a large homocyanin that is highly immunogenic like keyhole limpet hemocyanin (KLH) yet is more soluble. The carrier is rendered sulfhydryl-reactive by chemical modification with Sulfo-SMCC crosslinker, and the resulting maleimide-activated protein is then stabilized and lyophilized in phosphate buffer. Maleimide groups form covalent crosslinks with sulfhydryl (-SH) moieties on cysteine residues of peptides and other thiol-containing haptens. Numerous antigen molecules can be conjugated to each Blue Carrier Protein molecule to make them highly immunogenic and increase the likelihood of eliciting immunized animals to produce high-titer antisera to the epitopes of interest.


  • Optimized activation – specifications require that each lot is activated with more than 400 moles of sulhydryl-reactive maleimide per mole of carrier, ensuring consistently high levels of conjugatio

  • Sulfhydryl-reactive – engineered for conjugating cysteine-containing peptide antigens to make effective immunogens for high-titer antibody production

  • Simple, rapid procedure – complete the hapten-carrier conjugation reaction in two hours to yield sufficient immunogen for several injections and booster immunizations of host animals

  • High-quality carrier protein – Blue Carrier Protein is ultrapure Concholepas concholepas hemocyanin (CCH) prepared from molluscan hemolymph

  • Highly immunogenic and soluble – CCH has a high molecular mass that elicits a stronger immune response than BSA or ovalbumin