Lymphotoxin beta Receptor, Biotin, clone: eBio3C8 (3C8), eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 13-5671-80
Code : Z2
Additional Details : Weight : 0.25000kg
DescriptionDescription: The antibody reacts with mouse lymphotoxin-beta receptor (LTBR). Northern blot analysis of tissues from adult mice showed that expression levels of LTBR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. The tumor necrosis factor receptor-related protein is the human receptor for the heterotrimer of lymphotoxin-alpha and lymphotoxin-beta. This LT-alpha/LT-beta heterotrimer (LT-alpha1beta2) is assumed to take part in immunologic reactions by cell-cell contact, but does not bind to either TNFR1 (CD120alpha) or TNFR2 (CD120beta). LTBR is expressed by day 7 embryos, so it has been speculated that the LT-alpha/LT-beta receptor system may also have some function in early embryogenesis.Applications Reported: This eBio3C8 (3C8) antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBio3C8 (3C8) antibody has been tested by flow cytometric analysis of NIH/3T3 cells. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended to block Fc gamma-receptors with anti-mouse CD16/32 (cat. 14-0161), prior to staining to prevent non-specific binding of eBio3C8. Furthermore, it is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
|Lymphotoxin beta Receptor|
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3|
|Store at 2-8°C. Do not freeze.|
For Research Use Only.