Lymphotoxin beta Receptor Rat anti-Mouse, Biotin, Clone: eBio3C8 (3C8), eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-5671-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15209839

Quantity Price
1 £ 66.65 / 25µg
Estimated Shipment date
from Supplier 04-04-2017
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Description and Specification

Specification

Host Species Rat
Gene Alias LTbR,, LTbeta R
Species Reactivity Mouse
Conjugate Biotin
Isotype IgG1
Format Conjugated
Primary or Secondary Primary
Quantity 25μg
Regulatory Status RUO
Concentration 0.5mg/mL
Storage Requirements Store at 2-8°C. Do not freeze.
Antigen Lymphotoxin beta Receptor
Clone eBio3C8 (3C8)
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry

The antibody reacts with mouse lymphotoxin-beta receptor (LTBR). Northern blot analysis of tissues from adult mice showed that expression levels of LTBR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. The tumor necrosis factor receptor-related protein is the human receptor for the heterotrimer of lymphotoxin-alpha and lymphotoxin-beta. This LT-alpha/LT-beta heterotrimer (LT-α1β2) is assumed to take part in immunologic reactions by cell-cell contact, but does not bind to either TNFR1 (CD120α) or TNFR2 (CD120β). LTBR is expressed by day 7 embryos, so it has been speculated that the LT-alpha/LT-beta receptor system may also have some function in early embryogenesis.