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Ly-6G Monoclonal Antibody (1A8-Ly6g), PE-eFluor™ 610, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£106.00 - £243.00

Specifications

Antigen Ly-6G
Clone 1A8-Ly6g
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15560577
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Affymetrix eBioscience
61-9668-80
25 μg
£106.00
25µg
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Estimated Shipment: 08-05-2024
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15570577
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Affymetrix eBioscience
61-9668-82
100 μg
£243.00
100µg
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Description

Description

Description: The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G, which is also known as Gr-1. Ly-6G is a 25-kDa GPI protein expressed exclusively by neutrophils. Studies suggest an important role in neutrophil infiltration, recruitment and migration. Ly-6G associates with B2 integrins CD11a and CD11b and can attenuate B2 integrin expression and function. The ligand for Ly-6G is currently unknown. Unlike the RB6-8C5 antibody, 1A8-Ly6g is reported to only bind to Ly-6G found on neutrophils. Moreover, 1A8-Ly6g has been used to deplete neutrophils and reported to have antagonist activity. Applications Reported: This 1A8-Ly6g antibody has been reported for use in flow cytometric analysis. Applications Tested: This 1A8-Ly6g antibody has been tested by flow cytometric analysis of mouse bone marrow cells. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. PE-eFluor™ 610 can be excited with laser lines from 488-561 nm and emits at 607 nm. We recommend using a 610/20 band pass filter (equivalent to PE-Texas Red™). Please make sure that your instrument is capable of detecting this fluorochome.

Ly-6G Monoclonal antibody specifically detects Ly-6G in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

Ly-6G
0.2 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
Ly6g
Primary
4° C, store in dark, DO NOT FREEZE!
Ly6g
1A8-Ly6g
Flow Cytometry
PE-eFluor 610
Rat
Mouse
P35461
546644
IgG2a κ
Affinity chromatography
Antibody
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For Research Use Only.