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Ly-6G (Gr-1) Rat anti-Mouse, Clone: 1A8-Ly6g, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-9668-85

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15517836

  • £182.82 / 500µg


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For Research Use Only.


Description

Description

The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G, which is also known as Gr-1. Ly-6G is a 25kDa GPI protein expressed exclusively by neutrophils. Studies suggest an important role in neutrophil infiltration, recruitment and migration. Ly-6G associates with B2 integrins CD11a and CD11b and can attenuate B2 integrin expression and function. The ligand for Ly-6G is currently unknown.

Unlike the RB6-8C5 antibody, 1A8-Ly6g is reported to only bind to Ly-6G found on neutrophils. Moreover, 1A8-Ly6g has been used to deplete neutrophils and reported to have antagonist activity.
Specifications

Specifications

Ly-6G (Gr-1)
1A8-Ly6g
Unlabeled
Purified
IgG2a
RUO
Primary
Murine
Functional Assay
1mg/mL
aqueous buffer, no sodium azide
Rat
500μg
Store at 2-8°C.
Monoclonal
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