Ly-6C Rat anti-Mouse, PE-Cy7, Clone: HK1.4, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-5932-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15508606

Quantity Price
1 £ 74.51 / 25µg
EU Stock 12
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Description and Specification

Specification

Conjugate PE-Cy7
Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Clone HK1.4
Regulatory Status RUO
Quantity 25μg
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Rat
Antigen Ly-6C
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Isotype IgG2c
Concentration 0.2mg/mL
Primary or Secondary Primary

The monoclonal antibody HK1.4 recognizes mouse Ly-6C, a GPI-linked protein of the Ly6 family. Ly-6C is found on monocytes/macrophages, endothelial cells and granulocytes as well as a subset of lymphocytes. Some variation of expression is found on different mouse strains in regards to expression on CD4 and CD8 lymphocytes. These correlate to 2 alleles both of which are recognized by HK1.4: Ly6c.1 found on C57Bl/6 and SJL cells which results in staining of both CD4 and CD8 cells while Ly6-C.2 found on BALB/c and 3H/He results in staining of CD8, but not CD4 cells.

In vitro addition with HK1.4 antibody can increase proliferation and stimulate cytokine release.