Ly-6C Rat anti-Mouse, Alexa Fluor 488, Clone: HK1.4, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-5932-82

Product Code. 15580227

Disclaimers:

For Research Use Only.

Description

The monoclonal antibody HK1.4 recognizes mouse Ly-6C, a GPI-linked protein of the Ly6 family. Ly-6C is found on monocytes/macrophages, endothelial cells and granulocytes as well as a subset of lymphocytes. Some variation of expression is found on different mouse strains in regards to expression on CD4 and CD8 lymphocytes. These correlate to 2 alleles both of which are recognized by HK1.4: Ly6c.1 found on C57Bl/6 and SJL cells which results in staining of both CD4 and CD8 cells while Ly6-C.2 found on BALB/c and 3H/He results in staining of CD8, but not CD4 cells.

In vitro addition with HK1.4 antibody can increase proliferation and stimulate cytokine release.

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Specifications

• Antigen: Ly-6C
• Clone: HK1.4
• Conjugate: Alexa Fluor 488
• Format: Conjugated
• Isotype: IgG2c
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Murine

• Applications: Flow Cytometry
• Concentration: 0.2mg/mL
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Host Species: Rat
• Quantity: 100μg
• Storage Requirements: Store at 2-8°C. Do not freeze. Light-sensitive material.
• Monoclonal or Polyclonal: Monoclonal