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Ly-6A/E (Sca-1) Rat anti-Mouse, Biotin, Clone: D7, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-5981-81

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15259969

  • £42.77 / 50µg


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Disclaimers:

For Research Use Only.


Description

Description

The D7 monoclonal antibody reacts with mouse Sca-1, an 18kDa member of the Ly-6 family of GPI-linked surface proteins. D7 reacts with both Ly-6E.1 and Ly-6A.2 molecules expressed by mouse hematopoietic stem cells, myeloid population and peripheral T and B cells. Non-activated splenocytes from Ly-6.2 strains including C57BL, SJL, 129, AKR, and others demonstrate higher frequency of D7-positive cells compared to the Ly-6.1 strains such as BALB/c, C3H, NZB and others. Sca-1 is expressed at high levels upon activation regardless of the Ly-6 haplotype. The Ly-6 family is involved in regulation and function of T cell activation. Sca-1 is a major phenotypic marker for mouse hematopoietic progenitor/stem cell subset.
Specifications

Specifications

Ly-6A/E (Sca-1)
D7
Biotin
Conjugated
IgG2a
RUO
Primary
Murine
Flow Cytometry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
50μg
Store at 2-8°C. Do not freeze.
Monoclonal
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