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Ly-49I Monoclonal Antibody (YLI-90), FITC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

£98.00 - £217.00

Specifications

Antigen Ly-49I
Clone YLI-90
Concentration 0.5 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15208289
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Affymetrix eBioscience
11-5895-82
100 μg
£98.00
100µg
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Estimated Shipment: 08-05-2024
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15218289
View Documents Promotion Details
Affymetrix eBioscience
11-5895-85
500 μg
£217.00
500µg
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Estimated Shipment: 08-05-2024
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Description

Description

Description: The YLI-90 monoclonal antibody reacts with the B6 mouse Ly-49I receptor. Ly49I, a member of the Ly49 family with inhibitory function, is a homodimer type II transmembrane protein and contains an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM). YLI-90 binds to subpopulations of NK, NKT and T cell lineages in the C57Bl/6 strain. This antibody does not bind to cells from BALB/c, SJL or AKR/J mice. Applications Reported: YLI-90 has been reported for use in flow cytometric analysis. Applications Tested: The YLI-90 antibody has been tested by flow cytometric analysis of C57Bl/6 and BALB/c mouse splenocytes and can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered.

Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells.
Specifications

Specifications

Ly-49I
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
5E6; Killer cell lectin-like receptor 3; killer cell lectin-like receptor subfamily A, member 9; Klra3; Klra9; Ly-49; Ly49C; Ly-49c; Ly49I; Ly49I receptor; Ly-49I receptor; LY49I1; Lymphocyte antigen 49c; Nk2.1; T-cell surface glycoprotein Ly-49C
Klra9
Primary
4° C, store in dark, DO NOT FREEZE!
Klra9
YLI-90
Flow Cytometry
FITC
Mouse
Mouse
0
16640
IgG1 κ
Affinity chromatography
Antibody
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