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LY 487379 hydrochloride, Tocris Bioscience™

Selective positive allosteric modulator of mGlu2 receptors

Brand:  Tocris (Bio-Techne) 328310

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13442714

  • £155.76 / 10mg

Estimated Shipment
01-07-2019

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Description

Description

Positive allosteric modulator selective for mGlu2 receptors. Potentiates glutamate-stimulated [35S]GTPγS binding (EC50 values are 1.7 and > 10 μM for mGlu2 and mGlu3 receptors respectively). Devoid of any activity at mGlu5 and mGlu7 receptors. Promotes cognitive flexibility in a rat model.
Specifications

Chemical Identifiers

353229-59-1
488.906
ly 487379 hydrochloride, ly-487379 hydrochloride, 2,2,2-trifluoro-n-4-2-methoxyphenoxy phenyl-n-3-pyridinylmethyl ethanesulfonamide hydrochloride, 2,2,2-trifluoro-n-4-2-methoxyphenoxy phenyl-n-pyridin-3-ylmethyl ethanesulfonamide hydrochloride, ly-487379 hydrochloride hplc, 2,2,2-trifluoro-n-4-2-methoxyphenoxy phenyl-n-pyridin-3-yl methyl ethane-1-sulfonamide-hydrogen chloride 1/1, n-4-2-methoxyphenoxy phenyl-n-2,2,2-trifluoroethylsulfonyl pyrid-3-ylmethylamine hydrochloride
2,2,2-trifluoro-N-[4-(2-methoxyphenoxy)phenyl]-N-(pyridin-3-ylmethyl)ethanesulfonamide;hydrochloride
C21H20ClF3N2O4S
LPWFRDWTOKLHJC-UHFFFAOYSA-N
56972206
COC1=CC=CC=C1OC2=CC=C(C=C2)N(CC3=CN=CC=C3)S(=O)(=O)CC(F)(F)F.Cl

Specifications

LY 487379 hydrochloride
353229-59-1
ly 487379 hydrochloride, ly-487379 hydrochloride, 2,2,2-trifluoro-n-4-2-methoxyphenoxy phenyl-n-3-pyridinylmethyl ethanesulfonamide hydrochloride, 2,2,2-trifluoro-n-4-2-methoxyphenoxy phenyl-n-pyridin-3-ylmethyl ethanesulfonamide hydrochloride, ly-487379 hydrochloride hplc, 2,2,2-trifluoro-n-4-2-methoxyphenoxy phenyl-n-pyridin-3-yl methyl ethane-1-sulfonamide-hydrogen chloride 1/1, n-4-2-methoxyphenoxy phenyl-n-2,2,2-trifluoroethylsulfonyl pyrid-3-ylmethylamine hydrochloride
COC1=CC=CC=C1OC2=CC=C(C=C2)N(CC3=CN=CC=C3)S(=O)(=O)CC(F)(F)F.Cl
488.906
488.91
10mg
C21H20ClF3N2O4S
LPWFRDWTOKLHJC-UHFFFAOYSA-N
2,2,2-trifluoro-N-[4-(2-methoxyphenoxy)phenyl]-N-(pyridin-3-ylmethyl)ethanesulfonamide;hydrochloride
56972206
>99%
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