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LY 341495, Tocris Bioscience™

Highly potent, selective group II antagonist

Brand:  Tocris (Bio-Techne) 1209/10

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13488873

  • £209.88 / 10mg


Estimated Shipment
03-10-2018
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Description

Description

Highly potent and selective group II metabotropic glutamate receptor antagonist (Ki/IC50 values are 2.3, 1.3, 173, 990, 6800, 8200 and 22000 nM for human mGlu2, mGlu3, mGlu8, mGlu7a, mGlu1a, mGlu5a and mGlu4a receptors respectively). Readily brain penetrant and active in vivo. Disodium salt (Cat. No. 4062) also available. Also available as part of the Group II mGlu Receptor Tocriset™, Group III mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™ .
Specifications

Chemical Identifiers

201943-63-7
353.374
(2S)-2-Amino-2-[(1S, 2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl) propanoic acid
C20H19NO5
VLZBRVJVCCNPRJ-KPHUOKFYSA-N
9819927

Specifications

LY 341495
10mg
C20H19NO5
VLZBRVJVCCNPRJ-KPHUOKFYSA-N
(1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]cyclopropane-1-carboxylic acid
9819927
201943-63-7
>98%
(2S)-2-Amino-2-[(1S, 2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl) propanoic acid
C1C(C1C(CC2C3=CC=CC=C3OC4=CC=CC=C24)(C(=O)O)N)C(=O)O
353.374
353.37
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