Ly-108 Mouse anti-Mouse, Clone: eBio13G3-19D (13G3-19D), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1508-82

100UG:ANTI-MOUSE LY-108 PURIFIED 100 UG

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15247247

Quantity Price
1 £ 182.0 / 100µg
Estimated Shipment date
from Supplier 20-02-2017
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Description and Specification

Specification

Antigen Ly-108
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias SLAM Family Receptor, SLAMF6, SLAM F6, Ly108
Host Species Mouse
Applications Flow Cytometry
Applications Immunoprecipitation
Applications Western Blotting
Isotype IgG2a
Quantity 100μg
Regulatory Status RUO
Species Reactivity Mouse
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone eBio13G3-19D (13G3-19D)
Concentration 0.5mg/mL
Conjugate Unlabeled

The eBio13G3-19D monoclonal antibody reacts with mouse Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is also known as NTB-A (NK cell, T cell, B cell antigen), and is expressed on NK, T cells, and B cells. Engagement of the Ly108 receptor enhances NK cell activity and expression of IFN-gamma, and contributes to the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. CD4+ T cells from Ly108 knock-out mice exhibit diminished ability to produce IL-4 and defective neutrophil functions.

Staining has not revealed any strain differences between C57BL/6 and BALB/c mice. Other strains have not been tested.