Ly-108 Mouse anti-Mouse, Clone: eBio13G3-19D (13G3-19D), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1508-80

Product Code. 15237247

Disclaimers:

For Research Use Only.

Description

The eBio13G3-19D monoclonal antibody reacts with mouse Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is also known as NTB-A (NK cell, T cell, B cell antigen), and is expressed on NK, T cells, and B cells. Engagement of the Ly108 receptor enhances NK cell activity and expression of IFN-gamma, and contributes to the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. CD4+ T cells from Ly108 knock-out mice exhibit diminished ability to produce IL-4 and defective neutrophil functions.

Staining has not revealed any strain differences between C57BL/6 and BALB/c mice. Other strains have not been tested.

Specifications

• Antigen: Ly-108
• Clone: eBio13G3-19D (13G3-19D)
• Conjugate: Unlabeled
• Format: Purified
• Host Species: Murine
• Quantity: 25μg
• Storage Requirements: Store at 2-8°C.
• Monoclonal or Polyclonal: Monoclonal

• Applications: Western Blot
• Concentration: 0.5mg/mL
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Gene Alias: SLAM Family Receptor, SLAMF6, SLAM F6, Ly108
• Isotype: IgG2a
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Murine