Ly-108 Mouse anti-Mouse, APC, Clone: 13G3-19D, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-1508-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15320690

Quantity Price
1 £ 164.47 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Primary or Secondary Primary
Quantity 100μg
Antigen Ly-108
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Isotype IgG2a
Host Species Mouse
Concentration 0.2mg/mL
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone eBio13G3-19D (13G3-19D)
Regulatory Status RUO
Conjugate APC
Gene Alias SLAM Family Receptor, SLAMF6
Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Format Conjugated

The eBio13G3-19D monoclonal antibody reacts with mouse Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is also known as NTB-A (NK cell, T cell, B cell antigen), and is expressed on NK, T cells, and B cells. Engagement of the Ly108 receptor enhances NK cell activity and expression of IFN-gamma, and contributes to the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. CD4+ T cells from Ly108 knock-out mice exhibit diminished ability to produce IL-4 and defective neutrophil functions.

Staining has not revealed any strain differences between C57BL/6 and BALB/c mice. Other strains have not been tested.