Ly-108 Mouse anti-Mouse, APC, Clone: 13G3-19D, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-1508-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15310690

Quantity Price
1 £ 66.65 / 25µg
EU Stock 1
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Description and Specification

Specification

Primary or Secondary Primary
Conjugate APC
Regulatory Status RUO
Format Conjugated
Isotype IgG2a
Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Clone eBio13G3-19D (13G3-19D)
Host Species Mouse
Concentration 0.2mg/mL
Gene Alias SLAM Family Receptor, SLAMF6
Quantity 25μg
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen Ly-108
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The eBio13G3-19D monoclonal antibody reacts with mouse Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is also known as NTB-A (NK cell, T cell, B cell antigen), and is expressed on NK, T cells, and B cells. Engagement of the Ly108 receptor enhances NK cell activity and expression of IFN-gamma, and contributes to the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. CD4+ T cells from Ly108 knock-out mice exhibit diminished ability to produce IL-4 and defective neutrophil functions.

Staining has not revealed any strain differences between C57BL/6 and BALB/c mice. Other strains have not been tested.