Tocris Bioscience™ LU AA33810

Potent NPY Y5 receptor antagonist

Description

Potent neuropeptide Y (NPY) Y5 receptor antagonist (Ki = 1.5 nM in vitro). Displays ≥ 3300-fold affinity for Y5 over Y1, Y2 and Y4 receptors. Also binds human 5-HT2B and 5-HT1A receptors (Ki values are 247 and 478 nM respectively). Exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity.

Specifications

• Purity: >98%
• Product Type: LU AA33810
• Molecular Weight (g/mol): 423.62
• Inhibitors: LU AA33810

For Research Use Only