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Lomeguatrib, Tocris Bioscience™

MGMT inhibitor

Brand:  RD Systems (Bio-Techne) 4359/50

Code : Z1

Additional Details : Weight : 0.00050kg

Quantity 50mg

 View more versions of this product

Product Code. 13444624

  • £715.89 / 50mg

Estimated Shipment date
from Supplier 25-11-2019

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Description

Description

Inhibitor of O6-methylguanine-DNA methyltransferase (MGMT); (IC50 = 0.009 μM in cell-free extracts from HeLa S3 cells); attenuates MGMT activity in vitro and in vivo. Enhances the antitumor activity of temozolomide (Cat. No. 2706) in both human melanoma and MCF-7 xenografts.
Specifications

Chemical Identifiers

192441-08-0
326.172
lomeguatrib, patrin 2, patrin-2, 6-4-bromothenyloxy-7h-purin-2-amine, 6-4-bromo-2-thienyl methoxy-9h-purin-2-amine, 6-4-bromothiophen-2-yl methoxy-7h-purin-2-amine, 6-4-bromo-2-thienyl methoxyl purin-2-amine, 1h-purin-2-amine, 6-4-bromo-2-thienyl methoxy, lomeguatrib inn, lomeguatrib inn:ban
6-[(4-bromothiophen-2-yl)methoxy]-7H-purin-2-amine
C10H8BrN5OS
JUJPKFNFCWJBCX-UHFFFAOYSA-N
3025944
C1=C(SC=C1Br)COC2=NC(=NC3=C2NC=N3)N

Specifications

50mg
192441-08-0
lomeguatrib, patrin 2, patrin-2, 6-4-bromothenyloxy-7h-purin-2-amine, 6-4-bromo-2-thienyl methoxy-9h-purin-2-amine, 6-4-bromothiophen-2-yl methoxy-7h-purin-2-amine, 6-4-bromo-2-thienyl methoxyl purin-2-amine, 1h-purin-2-amine, 6-4-bromo-2-thienyl methoxy, lomeguatrib inn, lomeguatrib inn:ban
C1=C(SC=C1Br)COC2=NC(=NC3=C2NC=N3)N
326.172
326.17
Lomeguatrib
C10H8BrN5OS
JUJPKFNFCWJBCX-UHFFFAOYSA-N
6-[(4-bromothiophen-2-yl)methoxy]-7H-purin-2-amine
3025944
>98%
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