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Linopirdine dihydrochloride, Tocris Bioscience™

KV7 (KCNQ) channel blocker

Brand:  Tocris (Bio-Techne) 199950

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13460374

  • £600.29 / 50mg


Estimated Shipment
21-12-2018
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Description

Description

Blocker of KV7 (KCNQ) voltage-gated potassium channels; blocks KV7.1 + 7.3 (KCNQ2 + 3)/ M-currents (IC50 = 4 - 7 μM) and KV7.1 (KCNQ1) homomeric channels (IC50 = 8.9 μM). Augments hippocampal ACh release and is a cognitive enhancer following oral administration in vivo.
Specifications

Chemical Identifiers

113168-57-3
464.39
linopirdine dihydrochloride, 1-phenyl-3,3-bis pyridin-4-ylmethyl indolin-2-one dihydrochloride, c26h21n3o.2hcl, 1,3-dihydro-1-phenyl-3,3-bis 4-pyridinylmethyl-2h-indol-2-one dihydrochloride, 3,3-bis 4-pyridylmethyl-1-phenylindolin-2-one dihydrochloride, 3,3-bis 4-pyridylmethyl-1-phenylindolin-2-one dihydrochloride
1-phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one;dihydrochloride
C26H23Cl2N3O
ZEVVHCGTTNRYOY-UHFFFAOYSA-N
14209557
C1=CC=C(C=C1)N2C3=CC=CC=C3C(C2=O)(CC4=CC=NC=C4)CC5=CC=NC=C5.Cl.Cl

Specifications

Linopirdine dihydrochloride
113168-57-3
linopirdine dihydrochloride, 1-phenyl-3,3-bis pyridin-4-ylmethyl indolin-2-one dihydrochloride, c26h21n3o.2hcl, 1,3-dihydro-1-phenyl-3,3-bis 4-pyridinylmethyl-2h-indol-2-one dihydrochloride, 3,3-bis 4-pyridylmethyl-1-phenylindolin-2-one dihydrochloride, 3,3-bis 4-pyridylmethyl-1-phenylindolin-2-one dihydrochloride
C1=CC=C(C=C1)N2C3=CC=CC=C3C(C2=O)(CC4=CC=NC=C4)CC5=CC=NC=C5.Cl.Cl
464.39
464.39
50mg
C26H23Cl2N3O
ZEVVHCGTTNRYOY-UHFFFAOYSA-N
1-phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one;dihydrochloride
14209557
>99%
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