LAP Mouse anti-Human, Clone: VB3A9, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-9823-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15208837

Quantity Price
1 £ 103.33 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Antigen LAP
Storage Requirements Store at 2-8°C.
Formulation aqueous buffer, no sodium azide
Primary or Secondary Primary
Isotype IgG1
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Clone VB3A9
Format Purified
Conjugate Unlabeled
Species Reactivity Human
Quantity 100μg
Gene Alias latency-associated peptide, LAP-TGFb
Concentration 1mg/mL
Host Species Mouse
Applications Immunoprecipitation
Applications Western Blotting

This VB3A9 monoclonal antibody recognizes human latency-associated peptide (LAP), also known as the TGF-β propeptide. Human LAP is a homodimer of 65-75kDa that is non-covalently associated with TGF-β and this complex is also referred to as the small latent complex (SLC). LAP can be covalently associated with latent TGF-β binding proteins (LTBP) through disulfide bonds, forming the large latent complex (LLC). The association of LAP with TGF-β facilitates its secretion and also renders TGF-β inactive.

VB3A9 has been reported to cross-react with non-human primate LAP, but does not cross-react with mouse LAP.