LAP Mouse anti-Human, Clone: VB3A9, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-9823-80

25UG:ANTI-HUMAN LAP FUNCTIONAL GRADE PURIFIED

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15298827

Quantity Price
1 £ 82.0 / 25µg
Estimated Shipment date
from Supplier 07-12-2016
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Description and Specification

Specification

Antigen LAP
Applications Immunoprecipitation
Applications Western Blotting
Clone VB3A9
Concentration 1mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, no sodium azide
Gene Alias latency-associated peptide, LAP-TGFb
Host Species Mouse
Isotype IgG1
Quantity 25μg
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

This VB3A9 monoclonal antibody recognizes human latency-associated peptide (LAP), also known as the TGF-β propeptide. Human LAP is a homodimer of 65-75kDa that is non-covalently associated with TGF-β and this complex is also referred to as the small latent complex (SLC). LAP can be covalently associated with latent TGF-β binding proteins (LTBP) through disulfide bonds, forming the large latent complex (LLC). The association of LAP with TGF-β facilitates its secretion and also renders TGF-β inactive.

VB3A9 has been reported to cross-react with non-human primate LAP, but does not cross-react with mouse LAP.