LAP Mouse anti-Human, Clone: VB3A9, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-9823-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg

Disclaimers: For Research Use Only.

Product Code. 15298827

Quantity Price
1 £ 54.42 / 25µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification


Concentration 1mg/mL
Regulatory Status RUO
Host Species Mouse
Applications Immunoprecipitation
Applications Western Blotting
Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal
Clone VB3A9
Format Purified
Gene Alias latency-associated peptide, LAP-TGFb
Antigen LAP
Formulation aqueous buffer, no sodium azide
Isotype IgG1
Quantity 25μg
Species Reactivity Human
Primary or Secondary Primary
Conjugate Unlabeled

This VB3A9 monoclonal antibody recognizes human latency-associated peptide (LAP), also known as the TGF-β propeptide. Human LAP is a homodimer of 65-75kDa that is non-covalently associated with TGF-β and this complex is also referred to as the small latent complex (SLC). LAP can be covalently associated with latent TGF-β binding proteins (LTBP) through disulfide bonds, forming the large latent complex (LLC). The association of LAP with TGF-β facilitates its secretion and also renders TGF-β inactive.

VB3A9 has been reported to cross-react with non-human primate LAP, but does not cross-react with mouse LAP.