LAP (Latency Associated peptide), Functional Grade, clone: VB3A9, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 16-9823-80
Code : Z2
Additional Details : Weight : 0.01000kg
DescriptionDescription: This VB3A9 monoclonal antibody recognizes human latency-associated peptide (LAP), also known as the TGF-beta propeptide. Human LAP is a homodimer of 65-75kDa that is non-covalently associated with TGF-beta and this complex is also referred to as the small latent complex (SLC). LAP can be covalently associated with latent TGF-beta binding proteins (LTBP) through disulfide bonds, forming the large latent complex (LLC). The association of LAP with TGF-beta facilitates its secretion and also renders TGF-beta inactive. VB3A9 has been reported to cross-react with non-human primate LAP, but does not cross-react with mouse LAP.Applications Reported: This VB3A9 antibody has been reported for use in immunoblotting (WB) and immunoprecipitation.Applications Tested: This VB3A9 antibody has been tested by immunoblot analysis of human platelets under reducing conditions at 5μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay.Storage and handling: Use in a sterile environment.Filtration: 0.2μm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.
|PBS with no preservative; pH 7.2|
|CED, DPD1, LAP, TGFB, TGFbeta|
|Store at 2-8°C.|
For Research Use Only.