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LAMP5 (BAD-LAMP), clone: 34.2, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9778-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15587676

  • £76.26 / 25µg


EU Stock 6
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Description

Description

The monoclonal antibody 34.2 recognizes human lysosome-associated membrane protein 5 (LAMP5), a member of the LAMP family. LAMP5 differs from other LAMP family members in that its expression is more restricted and is referred to as brain and dendritic cell-associated LAMP-like molecule (BAD-LAMP). In humans, BAD-LAMP is expressed in post-natal neurons and non-activated plasmacytoid dendritic cells. Expression in neurons is localized to intracellular vesicles distributed in specific microdomains along neurites and may play a role in endocytosis. BAD-LAMP is localized to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) of plasmacytoid dendritic cells and is lost upon TLR activation.This 34.2 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded tissue using high or low pH antigen retrieval and can be used at less than or equal to 1 μg/mL. This 34.2 antibody has been tested by western blot analysis of reduced SK-N-SH cell lysates and can be used at less than or equal to 5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

LAMP5
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q9UJQ1
LAMP5
IgG1, kappa
25μg
Store at 2-8°C.
Primary
24141
Western Blot
34.2
Unconjugated
LAMP5
Purified
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Human
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