Lamin A/C Mouse, Alexa Fluor 488, Clone: 4A7, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-9688-80

25UG Anti-Lamin A/C Alexa Fluor 488

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15550277

Quantity Price
1 £ 73.93 / 25µg
Estimated Shipment date
from Supplier 27-02-2017
Add to basket


Description and Specification

Specification

Antigen Lamin A/C
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias LMNA, LMNC
Host Species Mouse
Applications Immunocytochemistry
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Isotype IgG1
Quantity 25μg
Regulatory Status RUO
Species Reactivity Hamster, Human, Mouse, Rabbit
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone 4A7
Concentration 0.5mg/mL
Conjugate Alexa Fluor 488

The monoclonal antibody 4A7 recognizes human, mouse, rabbit and hamster lamin A/C. Lamins are nuclear intermediate filament proteins that provide framework for the nuclear envelope, maintain cell morphology, and protect the nucleus from mechanical, thermal, and oxidative stresses. Lamins also play a role in nuclear assembly, chromatin organization, DNA replication, RNA transcription, cell signaling, and apoptosis. Lamin C is a splice variant of Lamin A and both are A-type lamins. Lamin A and C are crucial for skeletal and cardiac development and function. Defects in A-type lamins result in cardiomyopathy, muscular dystrophy, peripheral neuropathy, lipodystrophy, restrictive dermopathy, and progeroid disorders.