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Tocris Bioscience™ L189

DNA ligase I, III and IV inhibitor

Brand:  Tocris Bioscience™ 356150

Code : Z1

Additional Details : Weight : 0.01000kg

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Product Code. 13433204

  • £515.97 / 50mg

Estimated Shipment date
from Supplier 24-03-2020

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Description

Description

DNA ligase I, III and IV inhibitor (IC 50 values are 5, 9 and 5 μM respectively) that blocks DNA binding (K i = 5 μM for DNA ligase I). Preferentially inhibits step 2 of the ligation reaction, and inhibits base excision repair (BER) and non-homologous end joining (NHEJ). Specifically sensitizes cancer cells to DNA damage and increases the cytotoxicity of DNA-damaging agents.
Specifications

Specifications

L189
L189
246.29
50mg
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