L-798,106, Tocris Bioscience™

Potent and highly selective EP3 antagonist

Brand:  Tocris (Bio-Techne) 334210

Product Code. 13462844

Description

Potent and highly selective prostanoid EP3 receptor antagonist (Ki values are 0.3, 916, > 5000 and > 5000 nM at EP3, EP4, EP1 and EP2 respectively). Attenuates sulprostone-induced inhibition of EFS-evoked twitch and contractile responses in vivo.

Chemical Identifiers

• CAS: 244101-02-8
• Molecular Weight (g/mol): 536.44
• Synonym: N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide

• Molecular Formula: C27H22BrNO4S
• InChI Key: ODTKFNUPVBULRJ-QINSGFPZSA-N
• PubChem CID: 71311930

Specifications

• Chemical Name or Material: L-798, 106
• Quantity: 10mg
• Molecular Formula: C27H22BrNO4S
• InChI Key: ODTKFNUPVBULRJ-QINSGFPZSA-N
• IUPAC Name: (Z)-N-(5-bromo-2-methoxyphenyl)sulfonyl-3-[2-(naphthalen-2-ylmethyl)phenyl]prop-2-enamide
• PubChem CID: 71311930

• CAS: 244101-02-8
• Purity Grade: >99%
• Synonym: N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide
• SMILES: COC1=C(C=C(C=C1)Br)S(=O)(=O)NC(=O)C=CC2=CC=CC=C2CC3=CC4=CC=CC=C4C=C3
• Molecular Weight (g/mol): 536.44
• Formula Weight: 536.44