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Tocris Bioscience™ L-755,507

Very potent and selective β3 partial agonist

Brand:  Tocris Bioscience™ 219750

Code : Z1

Additional Details : Weight : 0.01000kg

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Product Code. 13460774

  • £600.29 / 50mg


Estimated Shipment
03-09-2018
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Description

Description

Potent β3-adrenergic receptor partial agonist > 1000-fold selective over β1- and β2-adrenoceptors (EC50 values are 0.43, 580 and > 10000 nM for activation of cloned human β3-, β1- and β2-adrenoceptors respectively). Stimulates lipolysis in rhesus adipocytes in vitro (EC50 = 3.9 nM). Enhances CRISPR-mediated homology-directed repair (HDR) efficiency 2-3-fold for large fragments and ∽9-fold for point mutations, in human induced pluripotent stem cells (iPSCs).
Specifications

Specifications

L-755,507
>98
50mg
L-755,507
584.73
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