missing translation for 'onlineSavingsMsg'
Learn More

L-748,337, Tocris Bioscience™

Selective β3 antagonist

Brand:  Tocris (Bio-Techne) 276050

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

 View more versions of this product

Product Code. 13430544

  • £737.94 / 50mg

Estimated Shipment date
from Supplier 03-04-2020

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Competitive β3-adrenoceptor antagonist that displays selectivity over β1 and β2 receptors (Ki values are 4.0, 204 and 390 nM for β3-, β2- and β1-adrenoceptors respectively). Inhibits cAMP accumulation in response to isoproterenol (IC50 = 6 nM). Reduces iNOS expression, attenuates nitric oxide-induced cell proliferation and induces apoptosis in a melanoma cell line.
Specifications

Chemical Identifiers

244192-94-7
497.61
n-3-2s-2-hydroxy-3-2-4-phenylsulfonyl amino phenyl ethyl amino propoxy phenyl methyl-acetamide, d03vhk, n-3-2s-2-hydroxy-3-2-4-phenylsulfonylamino phenyl ethylamino propoxy phenyl methyl acetamide
N-[[3-[(2S)-3-[2-[4-(benzenesulfonamido)phenyl]ethylamino]-2-hydroxypropoxy]phenyl]methyl]acetamide
C26H31N3O5S
AWIONHVPTYTSHZ-DEOSSOPVSA-N
10028830
CC(=O)NCC1=CC(=CC=C1)OCC(CNCCC2=CC=C(C=C2)NS(=O)(=O)C3=CC=CC=C3)O

Specifications

50mg
244192-94-7
n-3-2s-2-hydroxy-3-2-4-phenylsulfonyl amino phenyl ethyl amino propoxy phenyl methyl-acetamide, d03vhk, n-3-2s-2-hydroxy-3-2-4-phenylsulfonylamino phenyl ethylamino propoxy phenyl methyl acetamide
CC(=O)NCC1=CC(=CC=C1)OCC(CNCCC2=CC=C(C=C2)NS(=O)(=O)C3=CC=CC=C3)O
497.61
497.61
L-748, 337
C26H31N3O5S
AWIONHVPTYTSHZ-DEOSSOPVSA-N
N-[[3-[(2S)-3-[2-[4-(benzenesulfonamido)phenyl]ethylamino]-2-hydroxypropoxy]phenyl]methyl]acetamide
10028830
>98%
Videos
Documents