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KLRG1 Monoclonal Antibody (13F12F2), PE-eFluor™ 610, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen 61948842
Additional Details : Weight : 0.01000kg
Description
Description: This 13F12F2 monoclonal antibody reacts with human killer cell lectin-like receptor subfamily G, member 1 (KLRG1), a type II transmembrane inhibitor receptor of the C-type lectin superfamily that contains an ITIM domain. This inhibitory receptor is expressed on subsets of gamma-delta T cells, NK (CD56dim), CD8+ and CD4+ T Cells. KLRG1 is expressed primarily by cells with an effector/memory phenotype that are short-lived, but capable of immediate effector cell function. Cadherin-E, -N, and -R are ligands for KLRG1. Cadherin/KLRG1 interaction inhibits cytolytic activity and proliferation. The percentage of KLRG1 positive cells can vary considerably, depending on antigen experience. The clones 13F12F2 and 13A2 appear to recognize a similar epitope based on cross-blocking studies. Applications Reported: This 13F12F2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 13F12F2 antibody has been pre-titrated and tested by flow cytometric analysis of human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
KLRG1 Monoclonal antibody specifically detects KLRG1 in Human samples. It is validated for Flow Cytometry.Specifications
KLRG1 | |
Monoclonal | |
5 μL/Test | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
Q96E93 | |
Klrg1 | |
Affinity chromatography | |
RUO | |
10219 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
13F12F2 | |
PE-eFluor 610 | |
Klrg1 | |
2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor | |
Mouse | |
100 Tests | |
Primary | |
Human | |
Antibody | |
IgG2a κ |