KLRG1 Mouse anti-Human, PE-Cy7, Clone: 13F12F2, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-9488-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15558666

Quantity Price
1 £ 213.39 / 100 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Applications Flow Cytometry
Quantity 100 tests
Monoclonal or Polyclonal Monoclonal
Conjugate PE-Cy7
Regulatory Status RUO
Gene Alias MAFA
Concentration 5μL (0.06μg)/test
Isotype IgG2a
Format Conjugated
Host Species Mouse
Antigen KLRG1
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Species Reactivity Human
Clone 13F12F2
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

This 13F12F2 monoclonal antibody reacts with human killer cell lectin-like receptor subfamily G, member 1 (KLRG1), a type II transmembrane inhibitor receptor of the C-type lectin superfamily that contains an ITIM domain. This inhibitory receptor is expressed on subsets of gamma-delta T cells, NK (CD56dim), CD8+ and CD4+ T Cells. KLRG1 is expressed primarily by cells with an effector/memory phenotype that are short-lived, but capable of immediate effector cell function. Cadherin-E, -N, and -R are ligands for KLRG1. Cadherin/KLRG1 interaction inhibits cytolytic activity and proliferation. The percentage of KLRG1 positive cells can vary considerably, depending on antigen experience.

The clones 13F12F2 and 13A2 appear to recognize a similar epitope based on cross-blocking studies.