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KLRG1, PE, clone: 13A2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-9487-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15577206

  • £87.94 / 25 tests


Estimated Shipment date
from Supplier 31-05-2018
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Description

Description

Description: This 13A2 monoclonal antibody reacts with human killer cell lectin-like receptor subfamily G, member 1 (KLRG1), a type II transmembrane inhibitor receptor of the C-type lectin superfamily that contains an ITIM domain. This inhibitory receptor is expressed on subsets of gamma-delta T cells, NK (CD56 im), CD8+ and CD4+ T Cells. KLRG1 is expressed primarily by cells with an effector/memory phenotype that are short-lived, but capable of immediate effector cell function. Cadherin-E, -N, and -R are ligands for KLRG1. Cadherin/KLRG1 interaction inhibits cytolytic activity and proliferation. The percentage of KLRG1 positive cells can vary considerably, depending on antigen experience.The clones 13F12F2 and 13A2 appear to recognize a similar epitope based on cross-blocking studies.Applications Reported: This 13A2 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 13A2 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

KLRG1
Monoclonal
5μl/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Q96E93
2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE, C-type lectin domain family 15 member A, C-type lectin domain family 15, member A, ITIM-containing receptor MAFA-L, MAFA-like receptor, killer cell lectin-like receptor subfamily G member 1, mast cell function-associated antigen (ITIM-containing)
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
13A2
PE
KLRG1
Conjugated
KLRG1
IgG1
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
10219
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