KLRG1 Mouse anti-Human, PE, Clone: 13A2, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9487-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15577206

Quantity Price
1 £ 84.99 / 25 tests
Estimated Shipment date
from Supplier 02-05-2017
Add to basket


Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25 tests
Concentration 5μL (0.25μg)/test
Applications Flow Cytometry
Regulatory Status RUO
Antigen KLRG1
Isotype IgG1
Conjugate PE
Gene Alias MAFA
Species Reactivity Human
Primary or Secondary Primary
Host Species Mouse
Clone 13A2
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

This 13A2 monoclonal antibody reacts with human killer cell lectin-like receptor subfamily G, member 1 (KLRG1), a type II transmembrane inhibitor receptor of the C-type lectin superfamily that contains an ITIM domain. This inhibitory receptor is expressed on subsets of gamma-delta T cells, NK (CD56 im), CD8+ and CD4+ T Cells. KLRG1 is expressed primarily by cells with an effector/memory phenotype that are short-lived, but capable of immediate effector cell function. Cadherin-E, -N, and -R are ligands for KLRG1. Cadherin/KLRG1 interaction inhibits cytolytic activity and proliferation. The percentage of KLRG1 positive cells can vary considerably, depending on antigen experience.

The clones 13F12F2 and 13A2 appear to recognize a similar epitope based on cross-blocking studies.