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KLRG1 Mouse anti-Human, PE, Clone: 13A2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-9487-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15577206

  • £84.99 / 25 tests


Estimated Shipment date
from Supplier 31-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This 13A2 monoclonal antibody reacts with human killer cell lectin-like receptor subfamily G, member 1 (KLRG1), a type II transmembrane inhibitor receptor of the C-type lectin superfamily that contains an ITIM domain. This inhibitory receptor is expressed on subsets of gamma-delta T cells, NK (CD56 im), CD8+ and CD4+ T Cells. KLRG1 is expressed primarily by cells with an effector/memory phenotype that are short-lived, but capable of immediate effector cell function. Cadherin-E, -N, and -R are ligands for KLRG1. Cadherin/KLRG1 interaction inhibits cytolytic activity and proliferation. The percentage of KLRG1 positive cells can vary considerably, depending on antigen experience.

The clones 13F12F2 and 13A2 appear to recognize a similar epitope based on cross-blocking studies.
Description & Specifications

Specifications

KLRG1
13A2
PE
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
Conjugated
MAFA
IgG1
RUO
Primary
Human