KLRG1 Mouse anti-Human, APC, Clone: 13F12F2, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-9488-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15578246

Quantity Price
1 £ 91.11 / 25 tests
EU Stock 1
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Description and Specification

Specification

Conjugate APC
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Species Reactivity Human
Format Conjugated
Concentration 5μL (0.25μg)/test
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen KLRG1
Gene Alias MAFA
Applications Flow Cytometry
Quantity 25 tests
Regulatory Status RUO
Isotype IgG2a
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Clone 13F12F2

This 13F12F2 monoclonal antibody reacts with human killer cell lectin-like receptor subfamily G, member 1 (KLRG1), a type II transmembrane inhibitor receptor of the C-type lectin superfamily that contains an ITIM domain. This inhibitory receptor is expressed on subsets of gamma-delta T cells, NK (CD56dim), CD8+ and CD4+ T Cells. KLRG1 is expressed primarily by cells with an effector/memory phenotype that are short-lived, but capable of immediate effector cell function. Cadherin-E, -N, and -R are ligands for KLRG1. Cadherin/KLRG1 interaction inhibits cytolytic activity and proliferation. The percentage of KLRG1 positive cells can vary considerably, depending on antigen experience.

The clones 13F12F2 and 13A2 appear to recognize a similar epitope based on cross-blocking studies.