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KLRG1 Monoclonal Antibody (2F1), PE-Cyanine7, eBioscience™, Invitrogen™

Syrian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 25-5893-82

154.00 GBP valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15320990

  • £231.00 / 100µg
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Description

Description

Description: This 2F1 monoclonal antibody reacts with the mouse Killer cell Lectin-like Receptor G1 (KLRG1), also known as Mast cell Function-associated Antigen (MAFA). KLRG1 is a homodimer of glycosylated 30-38 kDa subunits and contains a cytoplasmic motif similar to the immunoreceptor tyrosine-based inhibitory motif (ITIM). Rat MAFA was identified as an antigen specific to rat mast cells; however, the expression of mouse KLRG1/MAFA using 2F1 has not been detected on the surface of mouse mast cell lines, bone marrow-derived mast cells, or peritoneal mast cells. This antigen is expressed on approximately one-third of mouse NK cells and a subset of T cells. MHC class I molecules regulate KLRG1 via interactions with class I-specific inhibitory Ly49 molecules and SHP-1 signaling. Although KLRG1 and Ly49 are both lectin-like inhibitory receptors that are regulated by class I MHC expression, the effects of this on cell surface expression of these molecules are opposing, and the underlying regulatory mechanisms distinct. Applications Reported: This 2F1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 2F1 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL.

KLRG1 Monoclonal antibody specifically detects KLRG1 in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

KLRG1
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
O88713
Klrg1
Affinity chromatography
RUO
50928
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
2F1
PE-Cyanine7
Klrg1
2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor
Syrian Hamster
100 μg
Primary
Mouse
Antibody
IgG
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