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KLRG1 Syrian Hamster anti-Mouse, APC-eFluor® 780, Clone: 2F1, eBioscience™

Syrian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 47-5893-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15599586

  • £87.00 / 25µg

Estimated Shipment date
from Supplier 25-02-2020

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Description

Description

Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. APC-eFluor® 780 emits at 780 nm and is excited with the Red laser (633 nm). Please make sure that your instrument is capable of detecting this fluorochome. Light sensitivity: This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (cat. 00-8222) (100 µL of cell sample + 100 µL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (cat. 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 633-647 nm; Emission: 780 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered. KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1. KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells. NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.
Specifications

Specifications

KLRG1
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
O88713
2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE, C-type lectin domain family 15 member A, C-type lectin domain family 15, member A, ITIM-containing receptor MAFA-L, MAFA-like receptor, killer cell lectin-like receptor subfamily G member 1, mast cell function-associated antigen (ITIM-containing)
Syrian Hamster
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
2F1
APC-eFluor™ 780
Klrg1
Liquid
Klrg1
IgG
25 μg
4° C, store in dark, DO NOT FREEZE!
Primary
50928
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