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KC 12291 hydrochloride, Tocris Bioscience™

Orally active atypical Na+ channel blocker; cardioprotective

Brand:  Tocris (Bio-Techne) 325110

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13462654

  • £178.20 / 10mg


Estimated Shipment
27-11-2018
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Description

Description

Orally active atypical voltage-gated sodium channel blocker. Inhibits sustained sodium currents (INaL) and prevents diastolic contracture in isolated atria in vitro (IC50 values are 9.6 and 0.55 - 0.79μM respectively). Displays anti-ischemic, bradycardic and cardioprotective activity in vivo.
Specifications

Chemical Identifiers

181936-98-1
449.994
kc 12291 hydrochloride, 3,4-dimethoxy-n-methyl-n-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propyl benzeneethanamine hydrochloride, 3,4-dimethoxy-n-methyl-n-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propyl benzeneethanaminehydrochloride, n-3,4-dimethoxyphenethyl-n-methyl-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propan-1-amine hydrochloride, 2-3,4-dimethoxyphenyl ethyl methyl 3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propyl amine hydrochloride, n-2-3,4-dimethoxyphenyl ethyl-n-methyl-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propan-1-amine-hydrogen chloride 1/1
N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-3-[(5-phenyl-1,2,4-thiadiazol-3-yl)oxy]propan-1-amine;hydrochloride
C22H28ClN3O3S
KIJPRQYBNQKUAU-UHFFFAOYSA-N
22902387
CN(CCCOC1=NSC(=N1)C2=CC=CC=C2)CCC3=CC(=C(C=C3)OC)OC.Cl

Specifications

KC 12291 hydrochloride
181936-98-1
kc 12291 hydrochloride, 3,4-dimethoxy-n-methyl-n-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propyl benzeneethanamine hydrochloride, 3,4-dimethoxy-n-methyl-n-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propyl benzeneethanaminehydrochloride, n-3,4-dimethoxyphenethyl-n-methyl-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propan-1-amine hydrochloride, 2-3,4-dimethoxyphenyl ethyl methyl 3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propyl amine hydrochloride, n-2-3,4-dimethoxyphenyl ethyl-n-methyl-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propan-1-amine-hydrogen chloride 1/1
CN(CCCOC1=NSC(=N1)C2=CC=CC=C2)CCC3=CC(=C(C=C3)OC)OC.Cl
449.994
449.99
10mg
C22H28ClN3O3S
KIJPRQYBNQKUAU-UHFFFAOYSA-N
N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-3-[(5-phenyl-1,2,4-thiadiazol-3-yl)oxy]propan-1-amine;hydrochloride
22902387
>97%
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