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JNJ 28871063 hydrochloride, Tocris Bioscience™

Potent ErbB receptor family inhibitor

Brand:  Tocris (Bio-Techne) 335250

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13462864

  • £719.00 / 50mg


Estimated Shipment
05-07-2018
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Description

Description

Potent and selective ErbB receptor family inhibitor (IC50 values are 21, 22 and 38 nM for ErbB4, EGFR and ErbB2 respectively). Displays potent growth inhibition of human cancer cell lines overexpressing ErbB2 in vitro (IC50 = 60 - 168 nM) and inhibits growth of human tumor xenografts in vivo. Brain penetrant and orally active.
Specifications

Chemical Identifiers

JNJ 28871063 hydrochloride
C24H27ClN6O3·HCl
519.42
5E-4-Amino-6-(4-benzyloxy-3-chlorophenylamino)pyrimidine-5-carboxaldehyde N-(2-morpholin-4-ylethyl) oxime hydrochloride

Specifications

JNJ 28871063 hydrochloride
>97%
519.42
5E-4-Amino-6-(4-benzyloxy-3-chlorophenylamino)pyrimidine-5-carboxaldehyde N-(2-morpholin-4-ylethyl) oxime hydrochloride
944342-90-9
C24H27ClN6O3·HCl
50mg
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