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JNJ 28871063 hydrochloride, Tocris Bioscience™

Potent ErbB receptor family inhibitor

Brand:  Tocris (Bio-Techne) 335250

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13462864

  • £689.88 / 50mg


Estimated Shipment
30-10-2018
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Description

Description

Potent and selective ErbB receptor family inhibitor (IC50 values are 21, 22 and 38 nM for ErbB4, EGFR and ErbB2 respectively). Displays potent growth inhibition of human cancer cell lines overexpressing ErbB2 in vitro (IC50 = 60 - 168 nM) and inhibits growth of human tumor xenografts in vivo. Brain penetrant and orally active.
Specifications

Chemical Identifiers

944342-90-9
519.427
5e-4-amino-6-4-benzyloxy-3-chlorophenylamino pyrimidine-5-carboxaldehyde n-2-morpholin-4-ylethyl oxime hydrochloride
4-N-(3-chloro-4-phenylmethoxyphenyl)-5-[(E)-2-morpholin-4-ylethoxyiminomethyl]pyrimidine-4,6-diamine;hydrochloride
C24H28Cl2N6O3
ZXKZRKQMKNRZNN-GZPZNDDGSA-N
17747413
C1COCCN1CCON=CC2=C(N=CN=C2NC3=CC(=C(C=C3)OCC4=CC=CC=C4)Cl)N.Cl

Specifications

JNJ 28871063 hydrochloride
944342-90-9
5e-4-amino-6-4-benzyloxy-3-chlorophenylamino pyrimidine-5-carboxaldehyde n-2-morpholin-4-ylethyl oxime hydrochloride
C1COCCN1CCON=CC2=C(N=CN=C2NC3=CC(=C(C=C3)OCC4=CC=CC=C4)Cl)N.Cl
519.427
519.42
50mg
C24H28Cl2N6O3
ZXKZRKQMKNRZNN-GZPZNDDGSA-N
4-N-(3-chloro-4-phenylmethoxyphenyl)-5-[(E)-2-morpholin-4-ylethoxyiminomethyl]pyrimidine-4,6-diamine;hydrochloride
17747413
>97%
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