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JNJ 10191584 maleate, Tocris Bioscience™

Selective H4 receptor antagonist; orally active

Brand:  Tocris (Bio-Techne) 244110

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13461214

  • £132.00 / 10mg


Estimated Shipment
02-07-2018
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Description

Description

Highly selective histamine H4 receptor silent antagonist; binds with high affinity to the human H4 receptor (Ki = 26 nM). > 540-fold selective over the H3 receptor (Ki = 14.1 μM). Inhibits mast cell and eosinophil chemotaxis in vitro with IC50 values of 138 and 530 nM respectively. Orally active in vivo.
Specifications

Chemical Identifiers

JNJ 10191584 maleate
C13H15ClN4O·C4H4O4
394.81
1-[(5-Chloro-1H-benzimidazol-2-yl)carbonyl]-4-methylpiperazine maleate

Specifications

JNJ 10191584 maleate
869497-75-6
C13H15ClN4O·C4H4O4
1-[(5-Chloro-1H-benzimidazol-2-yl)carbonyl]-4-methylpiperazine maleate
10mg
>99%
394.81
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