Jagged 2 Armenian Hamster anti-Mouse, eFluor 660, Clone: HMJ2-1, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-3392-82

100UG Anti-Mouse Jagged 2 eFluor 660

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg

Disclaimers: For Research Use Only.

Product Code. 15519936

Quantity Price
1 £232.00 / 100µg
Estimated Shipment date
from Supplier 26-10-2016
Add to basket

Description and Specification


Antigen Jagged 2
Applications Flow Cytometry
Clone HMJ2-1
Concentration 0.2mg/mL
Conjugate eFluor 660
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Jag2
Host Species Armenian Hamster
Isotype IgG
Quantity 100μg
Regulatory Status RUO
Species Reactivity Mouse, Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

This HMJ2-1 monoclonal antibody reacts with mouse Jagged-2, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g., Notch 1-4), Jagged-2 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by gamma-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Jagged-2 is expressed by thymic lymphoid and stromal cells, as well as macrophages and dendritic cells in the spleen.

Note: Staining of endogenous splenic dendritic (CD8+CD11c+) cells could only be consistently confirmed in cells isolated from C57BL/6, but not Balb/c, mice. Other strains have not been tested. The antiobdy has been reported to crossreact to rat and have blocking function.