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Jagged 2 Monoclonal Antibody (HMJ2-1), eFluor™ 660, eBioscience™, Invitrogen™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-3392-82

138.67 GBP valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15519936

  • £208.00 / 100µg
Estimated Shipment: 08-05-2024
to see stock.

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Description

Description

Description: This HMJ2-1 monoclonal antibody reacts with mouse Jagged-2, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g., Notch 1-4), Jagged-2 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by gamma-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Jagged-2 is expressed by thymic lymphoid and stromal cells, as well as macrophages and dendritic cells in the spleen. Note: Staining of endogenous splenic dendritic (CD8+CD11c+) cells could only be consistently confirmed in cells isolated from C57BL/6, but not Balb/c, mice. Other strains have not been tested. The antiobdy has been reported to crossreact to rat and have blocking function. Applications Reported: This HMJ2-1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This HMJ2-1 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. eFluor™ 660 is a replacement for Alexa Fluor™ 647.

Jagged 2 Monoclonal antibody specifically detects Jagged 2 in Mouse, Rat samples. It is validated for Flow Cytometry.
Specifications

Specifications

Jagged 2
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P97607, Q9QYE5
Jag2
Affinity chromatography
RUO
16450, 29147
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
HMJ2-1
eFluor 660
Jag2
D12Ggc2e; HJ2; JAG2; jagged 2; Jagged2; mJagged2-1; protein jagged-2; SER2; Serh; sm; syndactylism
Armenian Hamster
100 μg
Primary
Mouse, Rat
Antibody
IgG
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For Research Use Only.