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IOX 2, Tocris Bioscience™

Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor

Brand:  RD Systems (Bio-Techne) 4451/50

Code : Z1

Additional Details : Weight : 0.00010kg

Quantity 50mg

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Product Code. 13444784

  • £668.85 / 10mg

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Description

Description

Potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) (IC50 = 21 nM). Displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases JMJD2A, JMJD2C, JMJD2E and JMJD3. Cell permeable.
Specifications

Chemical Identifiers

931398-72-0
352.346
iox2, iox 2, iox2 glycine, 2-1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido acetic acid, 2-1-benzyl-4-hydroxy-2-oxoquinoline-3-carbonyl amino acetic acid, 1-benzyl-4-hydroxy-2-oxoquinolin-3-yl formamido acetic acid, d0wa3e, iox-2, iox hplc, 1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl glycine
2-[(1-benzyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]acetic acid
C19H16N2O5
CAOSCCRYLYQBES-UHFFFAOYSA-N
54685215
C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=C(C2=O)C(=O)NCC(=O)O)O

Specifications

IOX 2
C19H16N2O5
CAOSCCRYLYQBES-UHFFFAOYSA-N
2-[(1-benzyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]acetic acid
54685215
>99%
931398-72-0
iox2, iox 2, iox2 glycine, 2-1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido acetic acid, 2-1-benzyl-4-hydroxy-2-oxoquinoline-3-carbonyl amino acetic acid, 1-benzyl-4-hydroxy-2-oxoquinolin-3-yl formamido acetic acid, d0wa3e, iox-2, iox hplc, 1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl glycine
C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=C(C2=O)C(=O)NCC(=O)O)O
352.346
352.34
50mg
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