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IOX 2, Tocris™

Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor

Brand:  Thermo Scientific Nunc 445110

Code : 76

Additional Details : Weight : 3.24400kg

Quantity 10mg

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Product Code. 10550962

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Description

Description

Potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) (IC50 = 21 nM). Displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases JMJD2A, JMJD2C, JMJD2E and JMJD3. Cell permeable.
Specifications

Chemical Identifiers

IOX 2
C19H16N2O5
352.34
N-[[1, 2-Dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]glycine

Specifications

IOX 2
>99%
352.34
10mg
931398-72-0
C19H16N2O5
N-[[1, 2-Dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]glycine
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