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Integrin Beta 7 Rat anti-Human, Mouse, PE-Cy7, Clone: FIB504, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 25-5867-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15588576

  • £72.77 / 25 tests


Estimated Shipment date
from Supplier 28-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The FIB504 monoclonal antibody reacts with human and mouse integrin beta 7. Integrin beta 7 is a 130 kD glycoprotein which associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Main ligands for integrin alpha 4 beta 7 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the main ligand of integrin alpha E beta 7 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response. The FIB504 antibody has been reported to have blocking activity.
Description & Specifications

Specifications

Integrin Beta 7
FIB504
PE-Cy7
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
Conjugated
Integrin b7, ITGB7
IgG2a
RUO
Primary
Murine