Integrin Beta 5 Mouse, FITC, Clone: KN52, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-0497-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15526416

Quantity Price
1 £ 66.65 / 25 tests
EU Stock 3
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Description and Specification

Specification

Concentration 5μL (0.125μg)/test
Primary or Secondary Primary
Clone KN52
Isotype IgG1
Monoclonal or Polyclonal Monoclonal
Conjugate FITC
Quantity 25 tests
Gene Alias Integrin b5, ITGB5
Host Species Mouse
Applications Flow Cytometry
Antigen Integrin Beta 5
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Format Conjugated
Species Reactivity Hamster, Human, Mouse
Regulatory Status RUO

The KN52 antibody reacts with human integrin beta 5, an approximately 100,000 Mr (reduced) and 95,000 Mr (nonreduced) a member of the integrin family. Only a single alpha chain, the alpha v subunit, associates with the integrin beta 5 to form the vitronectin receptor complex. Integrin alpha v/beta 5 complex also binds to the basic domain of Tat (he sequence RKKRRQRRR). The integrin beta 5 is found on carcinoma cell lines, hepatoma and fibroblast cell lines, and is absent from lymphoblastoid cells and platelets.

The KN52 monoclonal antibody has been shown to inhibit migration.