Integrin Beta 5 Mouse, FITC, Clone: KN52, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 11-0497-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15536416

Quantity Price
1 £ 170.59 / 100 tests
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Gene Alias Integrin b5, ITGB5
Species Reactivity Hamster, Human, Mouse
Host Species Mouse
Isotype IgG1
Clone KN52
Regulatory Status RUO
Antigen Integrin Beta 5
Concentration 5μL (0.125μg)/test
Quantity 100 tests
Primary or Secondary Primary
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal or Polyclonal Monoclonal
Conjugate FITC
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Format Conjugated

The KN52 antibody reacts with human integrin beta 5, an approximately 100,000 Mr (reduced) and 95,000 Mr (nonreduced) a member of the integrin family. Only a single alpha chain, the alpha v subunit, associates with the integrin beta 5 to form the vitronectin receptor complex. Integrin alpha v/beta 5 complex also binds to the basic domain of Tat (he sequence RKKRRQRRR). The integrin beta 5 is found on carcinoma cell lines, hepatoma and fibroblast cell lines, and is absent from lymphoblastoid cells and platelets.

The KN52 monoclonal antibody has been shown to inhibit migration.