Integrin beta 5, clone: KN52, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-0497-80
Code : Z2
Additional Details : Weight : 0.01000kg
DescriptionDescription: The KN52 antibody reacts with human integrin beta 5, an approximately 100,000 Mr (reduced) and 95,000 Mr (nonreduced) a member of the integrin family. Only a single alpha chain, the alpha v subunit, associates with the integrin beta 5 to form the vitronectin receptor complex. Integrin alpha v/beta 5 complex also binds to the basic domain of Tat (he sequence RKKRRQRRR). The integrin beta 5 is found on carcinoma cell lines, hepatoma and fibroblast cell lines, and is absent from lymphoblastoid cells and platelets.The KN52 monoclonal antibody has been shown to inhibit migration.Applications Reported: This KN52 antibody has been reported for use in flow cytometric analysis.Applications Tested: This KN52 antibody has been tested by flow cytometric analysis of Chinese Hamster Ovary (CHO), A549 and normal human peripheral blood cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
|Integrin Beta 5|
|PBS with 0.09% sodium azide; pH 7.2|
|CD61, GP3A, GPIIIa|
|Store at 2-8°C.|
For Research Use Only.