Integrin Beta 5 Mouse, Clone: KN52, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0497-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15277007

Quantity Price
1 £ 42.19 / 25µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Conjugate Unlabeled
Host Species Mouse
Regulatory Status RUO
Concentration 0.5mg/mL
Monoclonal or Polyclonal Monoclonal
Isotype IgG1
Format Purified
Primary or Secondary Primary
Species Reactivity Hamster, Human, Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C.
Gene Alias Integrin b5, ITGB5
Clone KN52
Quantity 25μg
Applications Flow Cytometry
Antigen Integrin Beta 5

The KN52 antibody reacts with human integrin beta 5, an approximately 100,000 Mr (reduced) and 95,000 Mr (nonreduced) a member of the integrin family. Only a single alpha chain, the alpha v subunit, associates with the integrin beta 5 to form the vitronectin receptor complex. Integrin alpha v/beta 5 complex also binds to the basic domain of Tat (he sequence RKKRRQRRR). The integrin beta 5 is found on carcinoma cell lines, hepatoma and fibroblast cell lines, and is absent from lymphoblastoid cells and platelets.

The KN52 monoclonal antibody has been shown to inhibit migration.