missing translation for 'onlineSavingsMsg'
Learn More

Integrin alpha 4 beta 7 (LPAM-1) Rat anti-Mouse, PerCP-eFluor™ 710, Clone: DATK32 (DATK-32), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-5887-82

Code : NEW

Additional Details : Weight : 0.09500kg

 View more versions of this product

Product Code. 15599296

  • £208.00 / 100µg

Estimated Shipment
03-11-2020

Please to purchase this item. Need a web account? Register with us today!


Description

Description

We recommend using a 710/50 bandpass filter, however, the 695/40 bandpass filter is an acceptable alternative. Please make sure that your instrument is capable of detecting this fluorochrome. Fixation: Samples can be stored in IC Fixation Buffer (cat. 00-8222) (100 µL cell sample + 100 µL IC Fixation Buffer) or 1-step Fix/Lyse Solution (cat. 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 488 nm; Emission: 710 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered. Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
Specifications

Specifications

Integrin alpha 4 beta 7 (LPAM-1)
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q00651, P26011
ITGB7, Gut homing receptor beta subunit, Integrin alpha-4/beta-7, Peyer patches-specific homing receptor LPAM-1, Itga4
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
DATK32 (DATK-32)
PerCP-eFluor™ 710
Itga4
Liquid
Itga4, Itgb7
IgG2a, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
16401, 16421
Videos
Documents

For Research Use Only.