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Insulin Mouse, eFluor 570, Clone: ICBTACLS, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 41-9769-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15578966

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance

Disclaimers:

For Research Use Only.


Specifications

Description

This ICBTACLS monoclonal antibody reacts with the hormone insulin, responsible for regulation of carbohydrate and fat metabolism. Blood glucose levels are maintained by insulin. Insulin secretion from pancreatic beta-cells within the islets of Langerhans results in uptake of excess glucose from the blood into organs and its storage in the form of glycogen. Patients with type 1 diabetes have an autoimmune destruction of insulin-producing beta-cells in the pancreas, resulting in insulin deficiency and elevated levels of blood glucose. Patients with type 2 diabetes have insulin resistance where insulin becomes less effective at reducing the amount of blood glucose. Insulin is also important for proper endothelial cell function in with respect to vascular elasticity in response to changing blood pressure and plays a role in cognition, learning, and memory.

The ICBTACLS antibody recognizes human, mouse, and rat insulin.
Description & Specifications

Specifications

Insulin
ICBTACLS
eFluor 570
Conjugated
IgG2a
RUO
Primary
Rat
Microscopy
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal