Insulin Mouse, Clone: ICBTACLS, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9769-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15527666

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Description and Specification

Specification

Host Species Mouse
Regulatory Status RUO
Species Reactivity Human, Mouse, Rat
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Microscopy
Applications Western Blotting
Primary or Secondary Primary
Isotype IgG2a
Monoclonal or Polyclonal Monoclonal
Antigen Insulin
Conjugate Unlabeled
Quantity 25μg
Format Purified
Storage Requirements Store at 2-8°C.
Clone ICBTACLS
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This ICBTACLS monoclonal antibody reacts with the hormone insulin, responsible for regulation of carbohydrate and fat metabolism. Blood glucose levels are maintained by insulin. Insulin secretion from pancreatic beta-cells within the islets of Langerhans results in uptake of excess glucose from the blood into organs and its storage in the form of glycogen. Patients with type 1 diabetes have an autoimmune destruction of insulin-producing beta-cells in the pancreas, resulting in insulin deficiency and elevated levels of blood glucose. Patients with type 2 diabetes have insulin resistance where insulin becomes less effective at reducing the amount of blood glucose. Insulin is also important for proper endothelial cell function in with respect to vascular elasticity in response to changing blood pressure and plays a role in cognition, learning, and memory.

The ICBTACLS antibody recognizes human, mouse, and rat insulin.